產(chǎn)品詳情
Cat#:146P18
序列(三字母):H-Ala-Pro-Val-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-
Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His-Pro-Pro-Ser-Arg-Ala
-Glu-Gly-Gly-Gly-Lys-Gly-Lys-Thr-Ala-Leu-Gly-Ile-Leu-Asp-Leu
-Trp-Lys-Ala-Ile-Asp-Gly-Leu-Pro-Tyr-Pro-Gln-Ser-Gln-Leu-Ala
-Ser-OH trifluoroacetate salt
序列(單字母):APVHRGRGGWTLNSAGYLLGPVLHPPSRAEGGGKGKTALGIL
DLWKAIDGLPYPQSQLAS
類似名:GALP (porcine)
分子式:C???H???N??O??
分子量:6204.11
CAS#:245114-96-9
合成方法:Synthetic
存儲(chǔ)條件:-20 ± 5 °C
描述:This member of the galanin family has been isolated from
porcine hypothalamus. It is a 60 amino acid peptide that,
unlike galanin, has a non-amidated C-terminus. GALP
amino acid residues (9-21) are identical to the biologically
active N-terminal (1-13) portion of galanin. Receptor
binding studies revealed that GALP had a high affinity for
the galanin receptor 2 (GALR2; IC?? = 0.24 nM) and a lower
affinity for the GALR1 receptor (IC?? = 4.3 nM). GALP is
therefore an endogenous ligand that preferentially binds
the GALR2 receptor, whereas galanin is relatively
non-selective.
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