產(chǎn)品詳情
Cat#:173P25
序列(三字母):6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH? trifluoroacetate salt
序列(單字母):NBD-ε-aminocaproyl-RPKPLA-Nva-WK(DMACA)-NH?
類似名:NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH?
分子式:C??H???N??O??
分子量:1598.87
CAS#:945414-97-1
合成方法:Synthetic
存儲(chǔ)條件:-20 ± 5 °C
應(yīng)用:Cancer Research|
Inflammation Research
描述:NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH? (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10? M?1s?1 and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.
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