午夜理论片精品国产_a级毛片内射免费视频看_亚洲乱码一区二区三区卡在线观看_男女视频免费观看大全_少妇人妻在线视频_欧美日韩中文字幕在线琳琅_亚洲国产精品新一_国产成在线观看免费_ass年轻少妇bbwpic精品_老湿影视十分钟看

Cat#：176P06
序列（三字母）：H-Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala-OH trifluoroacetate salt
序列（單字母）：EKPKVEAYKAAAAPA
類似名：MBP (85-99) Peptide Antagonist
分子式：C??H???N??O??
分子量：1543.78
CAS#：444305-16-2
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Antigen-presenting Cells| Multiple Sclerosis
描述：The antagonistic 15-peptide EKPKVEAYKAAAAPA competes with MBP (85-99), the immunodominant epitope of myelin basic protein (MBP), a major candidate autoantigen in multiple sclerosis (MS), for binding to human leukocyte antigen (HLA)-DR2. The peptide also inhibits IL-2 secretion by MBP (85-99) specific T-cell clones and induces the production of Th2 cytokines by splenocytes. Furthermore, it could be shown that the peptide is able to suppress experimental autoimmune encephalomyelitis (EAE) in several models in a manner that is equipotent to random amino acid copolymers, such as Copaxone [poly (Y,E,A,K)n]. Therefore, this synthetic peptide might be suitable in the studying of MS.