產(chǎn)品詳情
Cat#:181P29
序列(三字母):H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH? trifluoroacetate salt
序列(單字母):GPSQPTYPGDNATPEQMARYYSALRRYINMA-Aib-YQYR-NH?
類(lèi)似名:(Gly1,Gln?·1?,Thr?·13,Tyr?,Asp1?,Asn11,Pro1?,Arg2?,Met3?,Ala31,Aib32)-Neuropeptide Y (human, rat)
分子式:C???H???N??O??S?
分子量:4207.73
CAS#:313988-89-5
合成方法:Synthetic
存儲(chǔ)條件:-20 ± 5 °C
應(yīng)用:Obesity Research
描述:This (Ala-Aib)-containing pancreatic peptide/neuropeptide Y chimera is a highly selective neuropeptide Y? receptor agonist. At this receptor this compound turned out to be 25-fold more potent than the derivative H-5084 (0.24 nM vs 6 nM) and three-fold more potent than the native ligand neuropeptide Y (H-6375) (0.24 nM vs 0.6 nM). This analog turned out to increase feeding approximately 2.5-fold more effective than neuropeptide Y.
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