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Cat#：205P34
序列（三字母）：H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH trifluoroacetate salt (Disulfide bond)
序列（單字母）：YCFAWKTFC
分子式：C??H??N??O??S?
分子量：1166.39
CAS#：647016-22-6
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
描述：Selective somatostatin receptor subtype sst4 agonist. In competitive radioligand displacement experiments using the non-selective radioligand ([12?I]-(Leu?,D-Trp22,Tyr2?)-Somatostatin-28, YCFAWKTFC exhibited a high affinity for sst4 with an IC?? value of 2.0 ± 0.5 nM. IC?? values for sst1, sst2, sst3, and sst5 were >1000 nM, 622 ± 85 nM, 624 ± 213 nM, and 692 ± 166 nM, respectively. The nonapeptide YCFAWKTFC may serve as a lead compound or tool for preclinical and clinical studies.