產(chǎn)品詳情
Cat#：211P31
序列（三字母）：H-Cys-Gly-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys-Ala-Glu-Cys-Cys-Gly-Gly-Ile-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Asn-Arg-NH? trifluoroacetate salt(Disulfide bonds between Cys1 and Cys1?/Cys? and Cys2?/Cys1? and Cys3?/Cys1? and Cys32)
序列（單字母）：CGPCFTTDHQMEQKCAECCGGIGKCYGPQCLCNR-NH?
分子式：C???H???N??O??S?
分子量：3676.27
CAS#：1926163-15-6
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Ion Channel Modulating Agents
描述：GaTx1 is a component of the venom of the yellow scorpion (Leiurus quinquestriatus hebraeus). The highly bridged 34-peptide, a chloride channel ligand, potently and reversibly inhibits cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels when the channels are in the interburst closed state. Since the toxin inhibits CFTR only when applied to the cytoplasmic side, it is unlikely that CFTR represents the native target. Manufactured and sold under license from Georgia Tech Research Corporation, USA; patent WO/2007/137163 (PCT/US2007/069243).
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