產(chǎn)品詳情
Cat#: 107P135
序列(三字母):H-Asp-Glu-Leu-Ala-Pro-Ala-Gly-Thr-Gly-Val-Ser-Arg-Glu-Ala-Val-Ser-Gly-Leu-Leu-Ile-Met-Gly-Ala-Gly-Gly-Gly-Ser-Leu-OH
序列(單字母):DELAPAGTGVSREAVSGLLIMGAGGGSL
類似名:APLP1-derived Aβ-like peptide (1-28)
分子式:C???H???N??O??S
分子量:2585.92
CAS#:1233876-42-0
合成方法:固相合成
存儲條件:-20 ± 5 °C,避光,干燥
應(yīng)用:Alzheimer′s Disease
描述:A highly sensitive biomarker for the production of Aβ 1-42 derived from the βAPP-like protein APLP1. The peptide is generated by the same proteolytic mechanism as Aβ42. Non-amyloidogenic APL1β28 can be detected in the CSF and its levels correlate with Aβ42 production. Its ratio to total APL1β (APL1β25, APL1β27, and APL1β28) is significantly increased in familial and sporadic cases of AD.
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