產(chǎn)品詳情
Cat#: 107P141
序列(三字母):H-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-OH
序列(單字母):VTGVTAVAQKTV
分子式:C??H??N??O??
分子量:1173.36
CAS #:332867-16-0
合成方法:固相合成
存儲(chǔ)條件:-20 ± 5 °C,避光,干燥
應(yīng)用:Alzheimer′s Disease
Parkinson’s Disease
描述:The deposition of α-synuclein (α-syn) fibrils in Lewy bodies is a characteristic feature of individuals with neurodegenerative disorders. The central hydrophobic region of α-synuclein, resembled by the peptide α-synuclein (71-82), is believed to be responsible for the protein aggregation. In addition, α-synuclein (71-82) forms amyloid fibrils of similar morphology to α-synuclein, suggesting that this region contributes to the fibrillogenic core of the full-length protein, referring to the studies of Madine and coworkers.
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