產(chǎn)品詳情
Cat#: 107P142
序列(三字母):Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2
序列(單字母):Ac-KDGIVNGVKA-NH2
分子式:C45H80N14O14
分子量:1041.2
合成方法:固相合成
存儲(chǔ)條件:-20 ± 5 °C,避光,干燥
應(yīng)用:Alzheimer′s Disease
Parkinson’s Disease
描述:Cheruvara and coworkers conducted a single step selection followed by two rounds of competition selection protein-fragment complementation assay (PCA) in order to derive α-synuclein (α-syn) binders capable of inhibiting aggregation. They isolated a 10-residue peptide antagonist, corresponding to the sequence of α-synuclein binding peptide that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
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