產(chǎn)品詳情
Cat#: 109P11
序列(三字母):H-Val-Tyr-Thr-Val-Gln-Ile-Cys-Thr-Lys-Ser-Gly-Asp-Trp-Lys-Ser-Lys-Cys-Phe-Tyr-Thr-Thr-OH (Disulfide bond)
序列(單字母):VYTVQICTKSGDWKSKCFYTT
分子式:C???H???N??O??S?
分子量:2456.83
CAS#:313642-01-2
合成方法:固相合成
存儲(chǔ)條件:-20 ± 5 °C,避光,干燥
應(yīng)用:Cardiovascular System & Diseases
Hematology
描述:Tissue factor (TF) is a transmembrane protein that functions as a cofactor for the serine protease factor VIIa in the initiation of blood coagulation in vivo. The 21-mer VYTVQICTKSGDWKSKCFYTT is a specific inhibitor of TF-dependent clotting. With an 11-membered disulfide-bridged ring it displayed a 4-fold enhancement of potency compared to the linear TF residue.
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