/Cancer Research Peptides (51)
/H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH trifluoroacetate salt (Disulfide bond)
產(chǎn)品詳情
Cat#: 121P41
序列(三字母):H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH trifluoroacetate salt (Disulfide bond)
序列(單字母):YCWSQYLCY
類似名:WP9QY, W9, YCWSQYLCY
分子式:C??H??N??O??S?
分子量:1226.4
CAS#:199999-60-5
合成方法:Synthetic
存儲條件:-20 ± 5 °C
應(yīng)用:Apoptosis & Necrosis
描述:The TNF-α antagonist WP9QY inhibited TNF-α mediated apoptosis and exhibited an IC?? of 5 μM in the binding assay. YCWSQYLCY is the smallest peptidomimetic developed to date that might be used as a lead compound for the next generation of non-peptidic inhibitors. The name WP9QY arises from the binding to the site observed in the TNF-β/TNF-receptor(I) complex designated WP9 and the introduction of the amino acids Gln and Tyr.
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